Metabolomic Biomarkers of Prostate Cancer: Prediction, Diagnosis, Progression, Prognosis, and Recurrence

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Metabolomic Biomarkers of Prostate Cancer: Prediction, Diagnosis, Progression, Prognosis, and Recurrence.

Metabolite profiling is being increasing employed in the study of prostate cancer as a means of identifying predictive, diagnostic, and prognostic biomarkers. This review provides a summary and critique of the current literature. Thirty-three human case-control studies of prostate cancer exploring disease prediction, diagnosis, progression, or treatment response were identified. All but one dem...

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Despite advances in the management of non-small cell lung cancer, it remains to be the leading cause of cancer-related deaths worldwide primarily because of diagnosis at a late stage with an overall 5-year survival rate of 17%. A reduction in mortality was achieved by low-dose computed tomography screening of high-risk patients. However, the benefit was later challenged by the high false positi...

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Emerging biomarkers for the diagnosis and prognosis of prostate cancer.

BACKGROUND Early detection of prostate cancer (CaP), the most prevalent cancer and the second-leading cause of death in men, has proved difficult, and current detection methods are inadequate. Prostate-specific antigen (PSA) testing is a significant advance for early diagnosis of patients with CaP. CONTENT PSA is produced almost exclusively in the prostate, and abnormalities of this organ are...

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Novel Biomarkers in Determining Prostate Cancer Diagnosis and Prognosis

Corresponding Author: Zuzana Varchulova Novakova Institute of Medical Biology, Genetics and Clinical Genetics, Faculty of Medicine, Comenius University, Bratislava, Slovakia E-mail: [email protected] Abstract: The clinical behavior and molecular pathology of prostate cancer is highly variable. Current “traditional” prognostic markers cannot reliably distinguish the potentially lif...

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A n international team of researchers believe they may have found, if not the smoking gun, at least a few DNA “bullets” that determine whether prostate cancer will become aggressive. A new biomarker study, which appeared in the Aug. 16, 2011, online edition of Cancer Epidemiology, Biomarkers, and Prevention, identified five inherited genetic variants associated with aggressive prostate cancer. ...

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ژورنال

عنوان ژورنال: Cancer Epidemiology Biomarkers & Prevention

سال: 2016

ISSN: 1055-9965,1538-7755

DOI: 10.1158/1055-9965.epi-15-1223